BETSEE (BioElectric Tissue Simulation Engine Environment) is the open-source cross-platform graphical user interface (GUI) for BETSE, a finite volume simulator for 2D computational multiphysics problems in the life sciences – including electrodiffusion, electro-osmosis, galvanotaxis, voltage-gated ion channels, gene regulatory networks, and biochemical reaction networks (e.g., metabolism).

Like BETSE, BETSEE is portably implemented in pure Python 3, continuously stress-tested with GitLab-CI × Appveyor + py.test, and permissively distributed under the BSD 2-clause license.

BETSEE is universally installable with either:

• [Recommended] pip, the standard Python package manager:

  pip3 install betsee

• Anaconda, a third-party Python package manager:

  conda config --add channels conda-forge
  conda install betsee

See our installation instructions for details. ¹

BETSEE is open-source software released under the permissive BSD 2-clause license. BETSEE contains third-party assets also released under BSD-compatible licenses, including:

• All Entypo+ icons distributed with BETSEE, kindly released under the permissive CC BY-SA 4.0 license by Daniel Bruce.
• All Noun Project icons distributed with BETSEE <BETSEE Noun Project icons_>__, kindly released under the permissive CC BY 3.0 license by various authors, including:
  • Maxim Kulikov, author of the salubrious bovine prominently displayed on this project page.
• All Open Iconic icons distributed with BETSEE <BETSEE Open Iconic icons_>__, kindly released under the permissive MIT license.

BETSE is formally described in our introductory paper. Third-party papers, theses, and other texts leveraging BETSEE (and hence BETSE) should ideally cite the following:

Alexis Pietak and Michael Levin, 2016. Exploring instructive physiological signaling with the bioelectric tissue simulation engine (BETSE)._ (Supplement)._² Frontiers in Bioengineering and Biotechnology,_ 4(55). ^{https://doi.org/10.3389/fbioe.2016.00055}

See also this list of BETSE-centric papers for additional material.

BETSEE comes courtesy a dedicated community of authors and contributors – without whom this project would be computationally impoverished, biologically misaligned, and simply unusable.

Thanks, all.

BETSEE is currently independently financed as a volunteer open-source project. Prior grant funding sources include (in chronological order):

1. For the three year period spanning 2017—2019, BETSEE was graciously associated with the Paul Allen Discovery Center at Tufts University and supported by a Paul Allen Discovery Center award from the Paul G. Allen Frontiers Group .