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Machine Learning and Systems Biology Research Department's Projects

adni_3dcnnvstda icon adni_3dcnnvstda

This is a summary of the model code used in "Back to the basics with inclusion of clinical domain knowledge - A simple, scalable and effective model of Alzheimer's Disease classification". It comprised the relevant 3D CNNs for hippocampus, patch and full inner brain image subsets, the TDA 2D CNN with relevant dense models to combine models trained on persistence images from different homological dimensions. Moreover, the models (GNN and LR) to combine multiple image patches are included, as well as the data splits in terms of ADNI database patient IDs (partitions).

alloimmunity-kinetics icon alloimmunity-kinetics

Code for "Pre-transplant kinetics of anti-HLA antibodies in patients on the kidney transplant waiting list."

arapheno icon arapheno

AraPheno source code for http://arapheno.1001genomes.org

ardiss icon ardiss

Automatic Relevance Determination for Imputation of Summary Statistics

baselepi icon baselepi

SEIR model framework used to describe the spread of the first SARS-CoV-2 wave within Basel-City

batchcorrectionpublicdata icon batchcorrectionpublicdata

Summary of the code published in 'reComBat: Batch effect removal in large-scale, multi-source omics data integration'.

casmap icon casmap

Detection of statistically significant combinations of SNPs in association mapping

ccsvm icon ccsvm

Confounder-corrected Classification with Support Vector Machines (Li et al., Bioinformatics 2011) http://goo.gl/Qz9Ap5

cofi icon cofi

Visualization and analysis of data sets containing time series with history information

dipha icon dipha

Automatically exported from code.google.com/p/dipha

easygwascore icon easygwascore

Computational Framework for Genome-Wide Association Studies and Meta-Studies in C/C++ with Python Interfaces

epistasis-glide icon epistasis-glide

A C and CUDA implementation of tabulating linear regression for an exhaustive pairwise interaction search on a CUDA enabled GPU (Kam-Thong et al., Human Heredity 2012) http://goo.gl/XE54ir

epistasis-lightbulb icon epistasis-lightbulb

Efficient algorithms and GPU implementations for genome-wide epistasis screens as described in (Achlioptas et al., KDD 2011) http://goo.gl/jX8kPi

findcomb icon findcomb

Scientifica app for finding the most significant combinations of features

fmri_cubical_persistence icon fmri_cubical_persistence

Code of our NeurIPS 2020 publication 'Uncovering the Topology of Time-Varying fMRI Data using Cubical Persistence'

genetic-heterogeneity-discovery-fastcmh icon genetic-heterogeneity-discovery-fastcmh

Genome-wide detection of intervals of genetic heterogeneity while accounting for categorical covariates (Llinares-López et al., Bioinformatics 2017) https://goo.gl/2QN2La

ggme icon ggme

Official repository for the ICLR 2022 paper "Evaluation Metrics for Graph Generative Models: Problems, Pitfalls, and Practical Solutions" https://openreview.net/forum?id=tBtoZYKd9n

graphhopper-kernels icon graphhopper-kernels

Scalable kernels for graphs with continuous attributes (Feragen et al., NIPS 2013) http://goo.gl/VxSfzZ

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