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R Package: canceRbits

Wrapper and helper functions commonly used by the Developmental Cancer Genomics group at St. Anna Children's Cancer Research Institute.

To install from github

To install the latest version

remotes::install_github(repo = 'cancerbits/canceRbits')

For reproducibility, e.g. in a dockerfile, use approaches below

To install a specific version given its tag

remotes::install_github(repo = 'cancerbits/canceRbits', ref = 'v0.1.2')

(All tags are listed here)

To install a specific commit

remotes::install_github(repo = 'cancerbits/canceRbits', ref = '10b959a')

(All commits are listed here)

Workflow for updating the package

  • Add/edit one or more .R files in R directory
    • Make sure to include roxygen documentation
  • run devtools::document()
  • add required packages to NAMESPACE file (if there are new ones)
  • (optional) Edit DESCRIPTION file (e.g. add your name, bump the version number)
  • (optional) Edit overall package documentation in R/canceRbits.R
  • (optional but strongly suggested) Add unit test for new functionality (in tests/testthat/)
  • check whether package is still OK via devtools::check(document = FALSE) or via Rstudio menu: 'Build' > 'Check Package'

Conventions

Exported functions have a cb_ prefix in their name.

Suggested reading

R packages by Hadley Wickham and Jenny Bryan

useful cheat sheet

Developmental Cancer Genomics's Projects

cancerbits icon cancerbits

Wrapper and helper functions commonly used by the Developmental Cancer Genomics group at St. Anna Children's Cancer Research Institute

cnn_graph icon cnn_graph

Convolutional Neural Networks on Graphs with Fast Localized Spectral Filtering

delegate icon delegate

Wrapper and helper functions to use bulk RNA-seq differential expression methods with single-cell data

keras-gcn icon keras-gcn

Keras implementation of Graph Convolutional Networks

kostelbal2023_nfatc1 icon kostelbal2023_nfatc1

R code used for the analysis of single-cell RNA-seq data presented in Köstel Bal et al., Blood, 2023

lch_hierarchy icon lch_hierarchy

Code for Epigenomics and Single-cell Sequencing Define a Developmental Hierarchy in Langerhans Cell Histiocytosis (Halbritter, Farlik, et al. 2019 Cancer Discov.)

santini2021_imprints icon santini2021_imprints

Code repository accompanying the paper by Santini, Halbritter, et al. (2021), Nat. Commun.

scde_benchmark icon scde_benchmark

Benchmark study for single-cell single-sample differential expression pipelines

shahin2021_ikzf2 icon shahin2021_ikzf2

Code repository accompanying the paper by Shahin et al. (2021), Sci. Immunol.

slice icon slice

A method for calculating single cell entropy and reconstructing cell differentiation lineage using single-cell RNA-seq data

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