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Computational Biology Group (CBG)'s Projects

5-virus-mix icon 5-virus-mix

Benchmarking data sets for haplotype reconstruction methods, sequenced with Illumina MiSeq, 454/Roche GSJunior, and Pacific Biosciences

bmi icon bmi

Mutual information estimators and benchmark

bmix icon bmix

BMix is a novel probabilistic method based on a constrained three-component mixture, which identifies high confidence T-to-C substitutions in PAR-CLIP data, and, based on these, reports putative RNA-protein cross-link sites.

bnpc icon bnpc

Bayesian non-parametric clustering (BnpC) of binary data with missing values and uneven error rates

conda_stats_gather icon conda_stats_gather

Used to track downloads of bioconda packages used by V-pipe, see: https://cbg-ethz.github.io/V-pipe/pipeline/

consensusfixer icon consensusfixer

Computes a consensus sequence with wobbles, ambiguous bases, and in-frame insertions, from a NGS read alignment.

covvfit icon covvfit

Fitness estimates of SARS-CoV-2 variants

cowwid icon cowwid

Procedure used fro the surveillance of SARS-CoV-2 genomic variants in wastewater.

ctc-scite icon ctc-scite

Computational method and analyses to study the clonality of circulating tumor cell clusters

dce icon dce

Finding the causality in biological pathways

demotape icon demotape

Computational demultiplexing of targeted single-cell sequencing (tapestri) data

epinem icon epinem

Epistatic Nested Effects Models - https://doi.org/10.1371/journal.pcbi.1005496 - https://bioconductor.org/packages/epiNEM/

epistasis-formulas icon epistasis-formulas

Computes higher-order interactions such as 2-way, 3-way,…, n-way interaction coordinates and some circuits in the n-locus case taking as input 2^n experimental measurements.

geneaccord icon geneaccord

GeneAccord: An R package to detect patterns of mutual exclusivity and co-occurrence on the clone level in a cohort of cancer patients

gesper icon gesper

Gene-Specific Phenotype EstimatoR

haploclique icon haploclique

Viral quasispecies assembly via maximal clique finding. A method to reconstruct viral haplotypes and detect large insertions and deletions from NGS data.

igb icon igb

IGB is a R script for computing individualized genetic barrier

indelfixer icon indelfixer

Iterative and very sensitive Next-Generation Sequencing (NGS) sequence alignment software. Accounting for large deletions and removes indels, causing frame shifts. In addition, only specific regions can be considered.

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