Comments (3)
This is now implemented in 52de5cf and will be included in the next release.
To use this function, simply do:
--target <bfile Prefix>,<fam file>
Note: No space
from prsice.
This doesn't work in the current build (see output below):
PRSice 2.0.10.beta (26 September 2017)
https://github.com/choishingwan/PRSice
(C) 2016-2017 Jack Euesden, Cathryn M. Lewis, Paul F. O'Reilly, Sam Choi
GNU General Public License v3
Thu Sep 28 09:41:24 2017
/mnt/lustre/groups/ukbiobank/usr/KCL_Data_Analyses/PRSice \
--base [path to base file] \
--target /mnt/lustre/datasets/ukbiobank/June2017/Genotypes/ukb_binary_v2,/mnt/lustre/groups/ukbiobank/KCL_Data/Genotypes/ukb1657_cal_chr1_v2_s488374.fam \
--type bed \
--binary-target F \
--out [redacted]\
--thread 4 \
--keep [path]/Keeps_For_PRSice.txt \
--bar-levels 0.05,1 \
--pheno-file [path]Pheno.txt \
--clump-kb 250 \
--clump-p 1 \
--clump-r2 0.1 \
--extract [path]_Includes.txt \
--stat BETA \
--chr CHR \
--A1 A1 \
--A2 A2 \
--snp SNP \
--bp BP \
--se SE \
--pvalue P \
--beta \
--fastscore
Loading Genotype file: /mnt/lustre/datasets/ukbiobank/June2017/Genotypes/ukb_binary_v2 (bed)
With external fam file: /mnt/lustre/groups/ukbiobank/KCL_Data/Genotypes/ukb1657_cal_chr1_v2_s488374.fam
terminate called after throwing an instance of 'std::runtime_error'
what(): Error: Cannot open bim file: /mnt/lustre/datasets/ukbiobank/June2017/Genotypes/ukb_binary_v2,/mnt/lustre/groups/ukbiobank/KCL_Data/Genotypes/ukb1657_cal_chr1_v2_s488374.fam.bim
This can be worked around by creating a symbolic link to the different components with a shared prefix
from prsice.
The update b22610e has now solve this problem. In addition, that should no longer complain about size of bed file when sex chromosome stuff is included (Haven't got an example file for me to test that though...)
from prsice.
Related Issues (20)
- [BUG] `sys/sysctl.h` is deprecated in glibc-2.3.2 HOT 2
- PRSet Background file HOT 4
- All the variants are excluded, No valid variants HOT 2
- [BUG]std::runtime_error when clumping HOT 1
- scores HOT 1
- Unrecognized Option HOT 4
- Error can't open base file HOT 2
- Reduce time HOT 2
- how to combine PRS from each chromosomes? HOT 15
- Set-based Clumping HOT 1
- Trying to run PRSice on files received by a collaborator but BGEN file is not being opened HOT 1
- INFO commands HOT 1
- Issue with the output files (.summary and .prsice files) HOT 1
- Empty Valid SNP ID
- Error: No valid variant remaining HOT 6
- Error: Invalid .bed file size for .bed HOT 4
- Error when inputing bgen files HOT 5
- Terminate called after throwing an instance of 'std::runtime_error'
- Issue with PRSice-v2 output HOT 3
- [support] replicable result on inidvidual level HOT 1
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from prsice.