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chrchang avatar chrchang commented on August 17, 2024

--assoc is based on allele counts. Males have only 1 allele per variant on chrX, while females have 2.

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Jingjiao-ma avatar Jingjiao-ma commented on August 17, 2024

so we calculate the number of allele1 in the case cohort like this:
female het_mut * 1 + female hom_mut * 2 + male mut * 1 is it right?

thank you
best

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