ericminikel Goto Github PK
Name: Eric Minikel
Type: User
Company: Prion Alliance
Bio: My mission in life is to prevent prion disease.
Twitter: cureffi
Location: Boston, MA
Blog: http://www.cureffi.org/
Name: Eric Minikel
Type: User
Company: Prion Alliance
Bio: My mission in life is to prevent prion disease.
Twitter: cureffi
Location: Boston, MA
Blog: http://www.cureffi.org/
Therapeutic trial of anle138b in mouse models of genetic prion disease
Characterization of the prion protein binding properties of antisense oligonucleotides
Antisense oligonucleotides extend survival of prion-infected mice
Data and code for a manuscript
Screening for small-molecule PrP binders
Comparison of callability in whole genomes vs. whole exoms
Miscellaneous scripts useful for chemical informatics
Code for making Markdown-compatible citations
PrP concentration in the central nervous system
List of FDA-approved drugs and CNS drugs with SMILES
Modulation of prion protein expression through cryptic splice site manipulation
Quantification of PrP in CSF as a pharmacodynamic biomarker
Cloud-based scalable and efficient single-cell genomics workflows
CureFFI.org
Compute diversity scores for all individuals with a variant allele
Evaluating potential drug targets through human loss-of-function genetic variation
Simulations and analyses of ascertainment bias in E200K genetic prion disease
HGMD mutations in ExAC exomes
Generate QC stats on individual exomes
A few quick analyses using Yaniv Erlich's FamiLinx dataset
Example repo for a git tutorial
NMR fragment screening
Refining the impact of genetic evidence on clinical success
Human genetic evidence enriches for side effects of approved drugs
Stuff for the wet lab. Scripts for designing CRISPR guide RNAs, primers and so on.
Analysis of GPI-anchored proteins
Comparison of coverage and genotypes in multiple datasets for GTEx
Analyses of various RNA-seq datasets related to Huntington's disease
Analysis of hydrocephalus reports in nusinersen
B9 vs. 129 SNPs in different lines of PrP knockout mice
A declarative, efficient, and flexible JavaScript library for building user interfaces.
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TypeScript is a superset of JavaScript that compiles to clean JavaScript output.
An Open Source Machine Learning Framework for Everyone
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Bring data to life with SVG, Canvas and HTML. 📊📈🎉
JavaScript (JS) is a lightweight interpreted programming language with first-class functions.
Some thing interesting about web. New door for the world.
A server is a program made to process requests and deliver data to clients.
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Some thing interesting about visualization, use data art
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Open source projects and samples from Microsoft.
Google ❤️ Open Source for everyone.
Alibaba Open Source for everyone
Data-Driven Documents codes.
China tencent open source team.