Comments (3)
@AntonioGPS Thanks for your quesiton.
Actually, the report contains all the Dynamic Fragmented Regions been evaluated, and not all the reported regions are DMR. I would use a script to adjsust p-value to FDRs, and then selected regions that are FDR<0.05.
Best,
Weilong Guo
from cgmaptools.
Hi,
I have similar question. Should we be also filtering on the basis of the methylation difference? That is, say should MethB-MethA be > 10% or more etc?
What would you suggest?
from cgmaptools.
I suggest to consider both "delta methylation level" and "p-values".
"delta methylation level" should consider two side: |MethA-MethB| > 10%
Best,
Weilong
from cgmaptools.
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