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James Watson's Projects

adaptiveantivenomdesign icon adaptiveantivenomdesign

A set of R scripts that run simulation studies of model and rule based adaptive dose-finding trials for novel antivenoms

bunching icon bunching

Estimating MIC of slowly eliminated antimalarials

chloroquine-concentration-fatality icon chloroquine-concentration-fatality

Pooled analysis of mortality and QRS widening in chloroquine self-poisoning patients and healthy volunteers: estimating safety of currently trialled chloroquine regimens

parasite_biomass icon parasite_biomass

Genetic association study using parasite biomass as a quantitative phenotype

phase2sims icon phase2sims

Simulations to help the design of phase 2 antiviral trials for SARS-CoV-2

platcov-ivermectin icon platcov-ivermectin

Results of the PLATCOV trial comparing Ivermectin and Regeneron with no intervention

recurrentvivax icon recurrentvivax

Probabilistically labelling recurrent vivax infections using time-to-event and microsatellite data

sensitive-plasmodium-structure icon sensitive-plasmodium-structure

Illustrative analysis showing how population genetic structure discovery in Plasmodium genetic data using principal coordinates analysis and hierarchical clustering is sensitive to the pairwise genetic distance and the clustering linkage function

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