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linzhi2013 avatar linzhi2013 commented on August 15, 2024

Hi Phismil,

In MitoZ paper,

We further annotate the putative control region in the case that the remaining interval region has a length ≥ 600 bp ([48] and all its PCGs, tRNA and rRNA are fully recovered.

"600 bp" is an arbitrary cutoff. We only consider annotating "the putative control region" when all other genes are recovered.

Do you mean that some species have control regions less than 600 bp? If this is case, I can add an option to allow users to change this value.

Cheers

from mitoz.

Phismil avatar Phismil commented on August 15, 2024

Dear Guanliang
Thank you for your kind response.
Yes, you are correct. Some species of invertebrates have a control region that is slightly shorter than 600 bp and it has been speculated that some might have more than one control region.
The addition of this option will be extremely useful and highly appreciated. I am using the singularity container, and I guess it might need some time for this option to be available in the container.
Cheers

from mitoz.

linzhi2013 avatar linzhi2013 commented on August 15, 2024

Thanks, @Phismil!

It would be great if you can provide a few publications about "some might have more than one control region." I'm interested in having a look at them.

from mitoz.

Phismil avatar Phismil commented on August 15, 2024

Hi,
As a mainly vertebrates geneticist, my knowledge is not the most updated, but I remember that we discussed this paper in a workshop. We have been told that it is very common in plants as well.
https://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-12-394
Cheers

from mitoz.

linzhi2013 avatar linzhi2013 commented on August 15, 2024

Hi Phismil ,

Thanks for it!!

from mitoz.

scintilla9 avatar scintilla9 commented on August 15, 2024

Hi @linzhi2013

Are there any updates or new features related to this issue?
I have a similar requirement for shorter control region.

Thanks!

from mitoz.

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