Regarding Ligand-receptor DB

[saeyslab]

Regarding Ligand-receptor DB

[browaeysrobin]

Hi @lagom2728

As mentioned in our preprint, we mainly combined two major resources: the Omnipath intercellular communication resource and this paper from Verschueren et al.: https://www.sciencedirect.com/science/article/pii/S0092867420306942?via%3Dihub. The lr_network object provides information which of these was used for a specific interaction. In case the interaction comes from Omnipath, you can use the OmnipathR functionality to check the underlying databases/papers describing a certain interaction. (In the near-future v2 release of multinichenetr, we will integrate example code to connect with OmnipathR., but for now I suggest you try this yourself.)

If you would have strong doubts about specific interactions, you can mail them to me privately so we can check how they ended up in the database.