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yil8 avatar yil8 commented on July 30, 2024

@lucananni93 Hi, map_lm.txt and map_tg.txt were selected and provided by the original authors of the LINCS program. They used to have a website that you can checkout, unfortunately, the website is not accessible anymore.

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lucananni93 avatar lucananni93 commented on July 30, 2024

Thank you. What about the redundancy between the set of landmark and target genes?

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yil8 avatar yil8 commented on July 30, 2024

@lucananni93 Honestly, I'm not sure about that, but as long as the prob id is different, it should be reasonable. I do remember they picked the landmark genes out of target genes through PCA, rather than some biological reasons. That might partially explain why there are overlaps in gene symbol.

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