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kegg-functional-analysis's Introduction

KEGG分析要点

KEGG文件层级结构

  • Pathway
    1. Pathway L1 (E.g Meatbolism)
    2. Pathway L2 (E.g Carbohydrate metabolism)
    3. pathway (E.g Glycolysis / Gluconeogenesis [PATH:ko00010])
    4. ko description
    Pathway层级解释

  • Module Module 是KO的功能合集,每个module 代表1个功能单元
    Module解释

KEGG数据预处理

  • KO的abundance: 计算相对丰度(Cell Host Microbe. 2023 Feb 8;31(2):273-287.e5. doi: 10.1016/j.chom.2023.01.001.)
  • ko的abundance: 同属于一个ko的KO加合(Cell Host Microbe. 2022 Oct 12;30(10):1450-1463.e8. doi: 10.1016/j.chom.2022.09.004.)

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