davidroad/ms-2smr

MS-2SMR

Running two-sample Mendelian randomization analyses on candidate risk genes of multiple sclerosis using cie-eQTL as instrumental variable.

GTEx data can be downloaded at: https://gtexportal.org/home/datasets

Reference

Hemani G, Zheng J, Elsworth B, Wade KH, Haberland V, Baird D, Laurin C, Burgess S, Bowden J, Langdon R et al: The MR-Base platform supports systematic causal inference across the human phenome. Elife 2018, 7.

Aguet F, Brown AA, Castel SE, Davis JR, He Y, Jo B, Mohammadi P, Park Y, Parsana P, Segrè AV et al: Genetic effects on gene expression across human tissues. Nature 2017, 550(7675):204-213.