egconley/anti-infective-dosage-calculator

Uses the Cockcroft-Gault Equation and the UW Medicine Renal Dosing Guidelines to render antimicrobial dosage for adults

anti-infective-dosage-calculator's Issues

vertical table view for mobile screen

add alphabetic footnote info to database

drug dropdown menu with option to filter by agent type

ability to select a new drug for same patient without re-entering patient info

duplicate rows rendering to table

HD radio button

show creatinine calculator form only if user doesn't select dialysis

display option to calculate and use adjusted body weight in form if recommended for drug

don't make user enter patient info for drugs that have the same dosing for all CrCl levels

add note to Voriconazole for dialysis

Although the package insert warns against use of IV Voriconazole in renal failure due to potential accumulation of the vehicle (SBECD), recent studies suggest no increase in adverse effects, including nephrotoxicity if used for less than < 28 days.

unit conversion

ability to convert input units:
serum creatinine - g/L ↔ g/dL ↔ mg% ↔ mg/mL
weight - kg ↔ lbs
height - cm ↔ in

ability to convert output units:
creatinine clearance - L/hr ↔ mL/hr ↔ mL/min

display Cockcroft-Gault equation with user input values

add Dalfopristin/Quinupristin dosing

Dosing for "Dalfopristin/Quinupristin"

Dosing: Adult
Skin and skin structure infection, complicated: IV: 7.5 mg/kg every 12 hours for at least 7 days

Bacteremia (methicillin-resistant Staphylococcus aureus) (off-label use): IV: 7.5 mg/kg every 8 hours (Liu 2011). Note: May be considered with vancomycin failure and when reduced susceptibility to vancomycin and daptomycin is present.

Infective endocarditis (methicillin-resistant Staphylococcus aureus), treatment (off-label use): IV: 7.5 mg/kg every 8 hours with or without additional antibiotics (Chesi 2006; ESC [Habib 2015]). Additional data is necessary to further define the role of quinupristin/dalfopristin in the treatment of this condition.

Infective endocarditis (multidrug-resistant Enterococcus faecium), treatment (off-label use): IV: 7.5 mg/kg every 8 hours with other antibiotics (eg, high-dose ampicillin or the combination of doxycycline and rifampin) (ESC [Habib 2015]; Matsumura 1998; Thompson 2003)

Intravascular catheter-associated bloodstream infection (methicillin-resistant coagulase negative staphylococci or ampicillin- and vancomycin-resistant E. faecium) (off-label use): IV: 7.5 mg/kg every 8 hours (IDSA [Mermel 2009])

Meningitis, bacterial and ventriculitis (alternative adjunct to systemic therapy for vancomycin-resistant E. faecium) (off- label use): Note: Use a preservative-free preparation:

Intrathecal: 1 to 4 mg daily (Garey 2001).

Intraventricular: 2 mg daily (Tush 1998; Williamson 2002) or 2 to 5 mg daily (IDSA [Tunkel 2004]; IDSA [Tunkel 2017]; Tan 2000).

When administered via a ventricular drain, clamp drain for 15 to 60 minutes after administration (allows solution to equilibrate in cerebrospinal fluid [CSF]) (IDSA [Tunkel 2017]). Note: Intraventricular administration is generally reserved for use in patients who fail parenteral therapy despite removal of CSF shunt or when CSF shunt cannot be removed (Baddour 2018).

Dosing: Renal Impairment: Adult
No dosage adjustment necessary.
Dosing: Hepatic Impairment: Adult
There are no dosage adjustments provided in the manufacturer’s labeling. However, pharmacokinetic data suggest dosage adjustment may be necessary.

make schema for UCLA Health dosage guidelines

https://asp.mednet.ucla.edu/files/view/UCLAAdultDosingCard.pdf

indication select button that appears only for relevant drugs