manandraj20 / ou-modelling-at-single-cell-resolution Goto Github PK
View Code? Open in Web Editor NEWwe use sc RNA-seq data across several tissues from 19 mammalian species to show that expression evolution across mammals is accurately modeled by the Ornstein–Uhlenbeck process, a commonly proposed model of continuous trait evolution.We apply this model to identify expression pathways under neutral, stabilizing, and directional selection.