owenustc/bnt162b2

Markdown version of Reverse Engineering the source code of the BioNTech/Pfizer SARS-CoV-2 Vaccine

The big BNT162b2 archive

All vaccine data here is sourced from this World Health Organization document.

This describes the RNA contents of the BNT162b2 SARS-CoV-2 vaccine. We should all be very grateful that BioNTech has shared this data with us. And of course we should also be grateful to the many many researchers that worked for decades to bring the state of the art to the point that such a vaccine could be developed. It is marvelous.

This GitHub repository is a companion to Reverse Engineering the source code of the BioNTech/Pfizer SARS-CoV-2 Vaccine and part 2.

In part 2 we find the challenge: Can we find an algorithm that turns the viral RNA into the vaccine RNA?

If so that would help explain how the vaccine is designed. It would also be useful for other researchers to turn viral RNA into RNA that gets converted into proteins efficiently.

Details are in part 2.

Data files

• ncov-s.fasta: the unprocessed RNA of the virus S protein
• vaccine-s.fasta: the unprocessed RNA of the vaccine S protein
• side-by-side.csv: the two files aligned, with virual and vaccine codons side by side