Comments (3)
from suppa.
Ah that's good to know. So there is not correction across genes, just within. Maybe suggest putting this statement in the docs, because users shouldn't expect FDR control across genes.
A few more suggestions: I think where you have family wise error rate in the docs, I think you should put something like "within-gene false discovery rate", because BH doesn't provide FWER control.
I think that you can drop alpha
as an argument. It's not used by multipletests
unless method='fdr_twostage'
:
I'm going to try out computing p-values per isoform, and then do my own aggregation. Interesting to know about the method differences also, I'll try out empirical vs classical.
from suppa.
from suppa.
Related Issues (20)
- ERROR:psiCalculator:No expression values have been buffered. HOT 3
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from suppa.