liuzhe30/mippi

Inferring the Effects of Protein Variants on Protein–protein Interactions with Interpretable Transformer Representations

Mutation Impact on Protein-Protein Interaction (MIPPI)

a deep transformer based neural network to predict mutation impact on protein-protein interaction.

• mippi_pkg -> Mutation Impact on Protein-Protein Interaction standalone package tool
• mippi -> source code of preprocessing and training

Requirements

• python 3.7+
• tensorflow 2.0+
• numpy, pandas

Cite as

Liu, Z., Qian, W., Cai, W., Song, W., Wang, W., Maharjan, D. T., ... & Lin, G. N. Inferring the Effects of Protein Variants on Protein–protein Interactions with Interpretable Transformer Representations. Research. DOI:10.34133/research.0219