Comments (2)
Would we want their clonality to contribute to estimates of clonality for their parent repertoires, or should it be reported separately? And when you say clonality, you mean the overall distribution of clone sizes, or the actual clone sizes for all the out-of-frames?
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To clarify, I think we need to report the clonal size of out-of-frame CDR3s somewhere; it shouldn't impact the clonality estimates for in-frame CDR3s.
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Related Issues (20)
- Feature request: save PCs from kPCA to log HOT 1
- Limitations in detecting out of frame TCRs HOT 3
- Single Chain parsed_seq Input Generating Blank Output File HOT 1
- Validation Data Missing Epitope Label HOT 2
- Amino Acid sequence inputs HOT 7
- How to use tcr-dist with only V gene-level information? HOT 6
- AssertionError HOT 4
- How to pair the alpha and beta chain reads from one TCR
- make_really_tall_trees.py script always running HOT 1
- text format cluster output for make_tall_trees.py HOT 2
- make_10x_clones_file.py issue HOT 2
- Bad CPU type HOT 4
- Estimation of TCRdiv HOT 8
- setup_gammadelta_db.py issue HOT 2
- usage with mixcr files HOT 8
- Issue with run_basic_analysis
- Losing Clones
- Apply tcr-dist on amino acid sequences HOT 1
- statistical method for testing degree of clustering/distance between groups of TCRs?
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