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pjvandehaar avatar pjvandehaar commented on August 14, 2024

I haven't thought of any good way to do it. Do you have a suggestion?

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Shicheng-Guo avatar Shicheng-Guo commented on August 14, 2024

Okay. I find a good solution for my own case. All my summary statistics is from UKB-GWS dataset, therefore, I can create my own sites-unannotated.tsv, rather than generated by pheweb sites since pheweb sites will loop 2000+ summary statistics (WGS-GWAS) files which takes quite long time.

I am wondering what will happen if my own sites-unannotated.tsv having some extra SNPs since REGENIE will ignore/remove some SNPs if MAF is lower than threshold.

Shicheng

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Shicheng-Guo avatar Shicheng-Guo commented on August 14, 2024

Interesting. looks like all the files in /generated-by-pheweb/sites are binary files which is not in old pheweb version.

-rw-r--r-- 1 sguo2 jan100 104K Sep  6 21:39 cpras-rsids.sqlite3
-rw-r--r-- 1 sguo2 jan100  18K Sep  6 21:39 sites-rsids.tsv
-rw-r--r-- 1 sguo2 jan100  13K Sep  6 21:39 sites-unannotated.tsv
-rw-r--r-- 1 sguo2 jan100  19K Sep  6 21:39 sites.tsv

In some old pheweb version, sites-unannotated.tsv is txt file which I think we can prepare by our own script.

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