structuralgenomicsconsortium/cnp27-sars-cov-2-nsp14

This project aims to develop a chemical probe of SARS-CoV2-NSP14 starting from a fragment screen

cnp27-sars-cov-2-nsp14's Issues

Purchased analogues of the original hit#3: RA- 0020081-01

We received the 9 purchased analogues of the original hit #3: RA- 0020081-01 from Mcule at UCL, the structures are as follow:

On 19th April, these analogues were sent to Nick Heaton's lab for testing against SARS-Cov-2-NSP14.

Purchased analogues of the original hit#1: RA-0020084-01

We received the 9 purchased analogues of the original hit RA-0020084-01 from Mcule at UCL, the structures are as follow:

On 19th April, these analogues were sent to Nick Heaton's lab for testing against SARS-Cov-2-NSP14.

Suggested analogues for synthesis

We are planning to make the commercially unavailable analogues in the lab at UCL aiming to get them by mid of May 2024 and to ship them accordingly to Nick Heaton lab for testing.

Purchased analogues of the original hit#1: RA-0020083-01

We received the 8 purchased analogues of the original hit #2: RA-0020083-01 from Mcule at UCL, the structures are as follow:

On 19th April, these analogues were sent to Nick Heaton's lab for testing against SARS-Cov-2-NSP14.