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beardymcjohnface avatar beardymcjohnface commented on June 21, 2024

Hi,
This is an interesting suggestion. Do you think having an option to use a custom primary database for the viruses of interest would work? The primary searches do essentially what you're suggesting, but for all viruses, and the secondary multi-kingdom searches weed out the false positives from this reduced pool of sequences.

from hecatomb.

dhoconno avatar dhoconno commented on June 21, 2024

Yep, absolutely. Depending on how much database prep is needed for the primary database, I could envision situations where providing a FASTA whitelist file would be simpler and wouldn't require modifying the virus database. If the primary database is already just a FASTA file of all viruses, then specifying a custom FASTA file of, say, all human viruses would be great.

from hecatomb.

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